Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12594.17 | 1.0136 | 1.0223 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12594.17 | 0.8538 | 0.7566 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12594.17 | 0.8538 | 0.7566 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12594.17 | 0.1416 | -0.5981 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12594.17 | 0.1416 | -0.5981 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12594.17 | 0.0074 | -0.9645 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12594.17 | 0.0074 | -0.9645 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12594.17 | 0.0087 | -0.9594 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12594.17 | 0.0087 | -0.9594 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12594.17 | 0.0084 | -0.9603 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12594.17 | 0.0084 | -0.9603 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14218.189 | 0.9695 | 0.9532 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14218.189 | 0.9695 | 0.9532 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14218.189 | 0.9297 | 0.8919 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14218.189 | 0.9297 | 0.8919 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14218.189 | 0.9614 | 0.9408 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14218.189 | 0.9614 | 0.9408 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14218.189 | 0.9473 | 0.9191 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14218.189 | 0.9473 | 0.9191 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14218.189 | 0.7232 | 0.5620 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14218.189 | 0.7232 | 0.5620 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14218.189 | 0.4015 | -0.0029 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14218.189 | 0.4015 | -0.0029 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14218.189 | 0.0089 | -0.9457 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14218.189 | 0.0089 | -0.9457 | 1.3111 |