Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14218.189 | 0.2343 | -0.3389 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14218.189 | 0.2343 | -0.3389 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14218.189 | 0.8826 | 0.8183 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14218.189 | 0.8826 | 0.8183 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14931.189 | 0.9554 | 0.8576 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14931.189 | 0.9554 | 0.8576 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14931.189 | 0.9909 | 0.9707 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14931.189 | 0.9909 | 0.9707 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14931.189 | 0.9409 | 0.8122 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14931.189 | 0.9409 | 0.8122 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14931.189 | 0.9626 | 0.8805 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14931.189 | 0.9626 | 0.8805 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14931.189 | 0.9882 | 0.9618 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14931.189 | 0.9882 | 0.9618 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14931.189 | 0.0581 | -0.9799 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14931.189 | 0.0581 | -0.9799 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14931.189 | 0.0176 | -0.9971 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14931.189 | 0.0176 | -0.9971 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14931.189 | 0.0141 | -0.9980 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14931.189 | 0.0141 | -0.9980 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14931.189 | 0.9903 | 0.9688 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14931.189 | 0.9903 | 0.9688 | 0.6183 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10642.145 | 1.0644 | 1.3860 | 0.3537 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10642.145 | 1.0644 | 1.3860 | 0.3537 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10642.145 | 0.9798 | 0.8879 | 0.3537 |