Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11854.159 | 1.0272 | 1.0429 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11854.159 | 0.9462 | 0.9144 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11854.159 | 0.9375 | 0.9005 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11854.159 | 0.4658 | 0.0927 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11854.159 | 0.0099 | -0.9481 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 11854.159 | 0.0076 | -0.9579 | 1.2639 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12056.159 | 0.9161 | 0.8173 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12056.159 | 0.9446 | 0.8792 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12056.159 | 0.9071 | 0.7977 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12056.159 | 0.9408 | 0.8710 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12056.159 | 0.8955 | 0.7726 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12056.159 | 0.9069 | 0.7973 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12056.159 | 0.1292 | -0.7867 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12056.159 | 0.0113 | -0.9851 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12056.159 | 0.0107 | -0.9859 | 0.9145 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12178.159 | 1.0579 | 1.1923 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12178.159 | 1.0339 | 1.1117 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12178.159 | 1.0177 | 1.0581 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12178.159 | 1.0608 | 1.2022 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12178.159 | 0.9812 | 0.9390 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12178.159 | 1.0367 | 1.1212 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12178.159 | 0.2652 | -0.7705 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12178.159 | 0.0160 | -0.9977 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12178.159 | 0.0174 | -0.9973 | 0.6130 | |
| BT-474 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12291.152 | 0.9218 | 0.7741 | 0.6792 |