Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7860.016 | 0.7036 | 0.1286 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7860.016 | 0.9591 | 0.8686 | 0.6145 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7911.016 | 1.0822 | 1.1222 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7911.016 | 0.9651 | 0.9473 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7911.016 | 1.0750 | 1.1117 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7911.016 | 1.0190 | 1.0284 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7911.016 | 0.9952 | 0.9928 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7911.016 | 0.7317 | 0.5816 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7911.016 | 0.0495 | -0.7910 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7911.016 | 0.0303 | -0.8555 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7911.016 | 0.0820 | -0.6946 | 1.3310 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7861.016 | 0.9256 | 0.9259 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7861.016 | 0.8801 | 0.8791 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7861.016 | 0.9665 | 0.9670 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7861.016 | 0.9487 | 0.9492 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7861.016 | 0.9781 | 0.9785 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7861.016 | 0.8779 | 0.8767 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7861.016 | 0.7716 | 0.7621 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7861.016 | 0.8323 | 0.8285 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7861.016 | 0.8433 | 0.8402 | 2.0473 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7862.016 | 1.0239 | 1.0360 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7862.016 | 1.0267 | 1.0403 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7862.016 | 1.0259 | 1.0391 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7862.016 | 0.9892 | 0.9837 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7862.016 | 1.0026 | 1.0039 | 1.3229 |