Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7862.016 | 1.0353 | 1.0531 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7862.016 | 0.8134 | 0.7108 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7862.016 | 0.8788 | 0.8139 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7862.016 | 0.7498 | 0.6087 | 1.3229 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7863.016 | 0.9626 | 0.9574 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7863.016 | 0.9758 | 0.9726 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7863.016 | 0.9590 | 0.9533 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7863.016 | 0.9620 | 0.9567 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7863.016 | 0.9863 | 0.9845 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7863.016 | 0.9401 | 0.9314 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7863.016 | 0.7992 | 0.7621 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7863.016 | 0.7239 | 0.6663 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7863.016 | 0.8263 | 0.7956 | 1.7699 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7864.016 | 0.8800 | 0.8355 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7864.016 | 0.9422 | 0.9216 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7864.016 | 0.9324 | 0.9081 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7864.016 | 0.9462 | 0.9271 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7864.016 | 1.0481 | 1.0641 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7864.016 | 0.9556 | 0.9399 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7864.016 | 0.7433 | 0.6387 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7864.016 | 0.7980 | 0.7189 | 1.4893 | ||
| Hs 578T | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7864.016 | 0.7573 | 0.6594 | 1.4893 | ||
| LY2 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7865.016 | 1.0175 | 1.0193 | 1.8047 | ||
| LY2 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7865.016 | 0.9399 | 0.9325 | 1.8047 | ||
| LY2 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7865.016 | 1.1893 | 1.2017 | 1.8047 |