Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7856.016 | 1.0544 | 1.1190 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7856.016 | 0.9814 | 0.9594 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7856.016 | 1.0673 | 1.1475 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7856.016 | 0.9789 | 0.9540 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7856.016 | 1.0241 | 1.0527 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7856.016 | 0.9420 | 0.8737 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7856.016 | 0.9520 | 0.8955 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7856.016 | 0.9114 | 0.8074 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7856.016 | 0.8807 | 0.7410 | 0.9156 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7857.016 | 0.9750 | 0.9584 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7857.016 | 0.9954 | 0.9923 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7857.016 | 1.0027 | 1.0044 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7857.016 | 0.9552 | 0.9253 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7857.016 | 0.9594 | 0.9324 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7857.016 | 0.9479 | 0.9132 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7857.016 | 0.9072 | 0.8447 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7857.016 | 0.9530 | 0.9217 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7857.016 | 0.8942 | 0.8227 | 1.2049 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7860.016 | 1.0491 | 1.1622 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7860.016 | 0.9975 | 0.9917 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7860.016 | 1.0488 | 1.1612 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7860.016 | 1.0064 | 1.0209 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7860.016 | 1.0122 | 1.0398 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7860.016 | 0.9678 | 0.8962 | 0.6145 | ||
| HCC70 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7860.016 | 0.9357 | 0.7950 | 0.6145 |