Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10997.143 | 0.6032 | -0.0905 | 0.6416 | |
| MCF7 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10997.143 | 0.5485 | -0.2157 | 0.6416 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10998.143 | 0.9477 | 0.8280 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10998.143 | 0.9168 | 0.7294 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10998.143 | 0.9735 | 0.9121 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10998.143 | 0.9406 | 0.8052 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10998.143 | 0.9887 | 0.9624 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10998.143 | 0.9154 | 0.7250 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10998.143 | 0.9137 | 0.7196 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10998.143 | 0.7507 | 0.2376 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10998.143 | 0.5596 | -0.2431 | 0.5976 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12206.143 | 1.0149 | 1.0279 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12206.143 | 0.9549 | 0.9153 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12206.143 | 0.9672 | 0.9384 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12206.143 | 0.9763 | 0.9555 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12206.143 | 0.9844 | 0.9708 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12206.143 | 0.9623 | 0.9292 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12206.143 | 0.8625 | 0.7413 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12206.143 | 0.7057 | 0.4428 | 1.0676 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12206.143 | 0.4941 | 0.0333 | 1.0676 | |
| MDA-MB-157 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12594.143 | 0.9956 | 0.9932 | 1.2787 | |
| MDA-MB-157 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12594.143 | 0.9637 | 0.9429 | 1.2787 | |
| MDA-MB-157 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12594.143 | 0.9621 | 0.9405 | 1.2787 | |
| MDA-MB-157 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12594.143 | 0.9873 | 0.9801 | 1.2787 | |
| MDA-MB-157 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 8 | uM | 12594.143 | 0.8286 | 0.7266 | 1.2787 |