Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10753.143 | 0.9134 | 0.8824 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10753.143 | 0.9286 | 0.9034 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10753.143 | 0.8585 | 0.8060 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10753.143 | 0.7659 | 0.6733 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 8 | uM | 10753.143 | 0.7862 | 0.7028 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 40 | uM | 10753.143 | 0.6868 | 0.5556 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 200 | uM | 10753.143 | 0.7361 | 0.6295 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 1000 | uM | 10753.143 | 0.6300 | 0.4684 | 1.4954 | |
| HCC1187 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 5000 | uM | 10753.143 | 0.2553 | -0.1974 | 1.4954 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12000.143 | 0.9166 | 0.8143 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12000.143 | 0.8859 | 0.7465 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12000.143 | 0.9743 | 0.9426 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12000.143 | 0.8577 | 0.6844 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 8 | uM | 12000.143 | 0.8903 | 0.7563 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 40 | uM | 12000.143 | 0.8455 | 0.6577 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 200 | uM | 12000.143 | 0.7683 | 0.4893 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 1000 | uM | 12000.143 | 0.6858 | 0.3116 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 5000 | uM | 12000.143 | 0.3873 | -0.3079 | 0.8939 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12084.143 | 0.9199 | 0.8800 | 1.3499 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12084.143 | 0.9065 | 0.8597 | 1.3499 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12084.143 | 0.8959 | 0.8437 | 1.3499 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12084.143 | 0.8943 | 0.8411 | 1.3499 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 8 | uM | 12084.143 | 0.9599 | 0.9403 | 1.3499 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 40 | uM | 12084.143 | 0.8247 | 0.7339 | 1.3499 | |
| HCC1395 | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 200 | uM | 12084.143 | 0.7763 | 0.6579 | 1.3499 |