Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9278.132 | 0.9700 | 0.8466 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9278.132 | 0.9826 | 0.9101 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9278.132 | 0.6620 | -0.3216 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9278.132 | 1.0168 | 1.0894 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9278.132 | 1.0120 | 1.0635 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9278.132 | 1.0479 | 1.2609 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9278.132 | 0.8539 | 0.3220 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9278.132 | 0.9670 | 0.8317 | 0.3815 | ||
| HCC1419 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9278.132 | 1.0039 | 1.0204 | 0.3815 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9294.019 | 0.9683 | 0.9266 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9294.019 | 0.9612 | 0.9102 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9294.019 | 0.8708 | 0.7030 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9294.019 | 0.8340 | 0.6198 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9294.019 | 0.7961 | 0.5344 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9294.019 | 0.7982 | 0.5392 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9294.019 | 0.7375 | 0.4041 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9294.019 | 0.6451 | 0.2019 | 0.8608 | ||
| HCC1428 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9294.019 | 0.3873 | -0.3357 | 0.8608 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7824.016 | 0.9110 | 0.8943 | 1.7164 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7824.016 | 0.9396 | 0.9287 | 1.7164 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7824.016 | 1.0006 | 1.0007 | 1.7164 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7824.016 | 0.9418 | 0.9313 | 1.7164 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7824.016 | 0.9310 | 0.9184 | 1.7164 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7824.016 | 0.8789 | 0.8551 | 1.7164 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7824.016 | 0.7695 | 0.7169 | 1.7164 |