Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14119.189 | 0.9826 | 0.9713 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14119.189 | 0.9944 | 0.9908 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14119.189 | 0.9944 | 0.9908 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14119.189 | 0.9646 | 0.9414 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14119.189 | 0.9646 | 0.9414 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14119.189 | 0.6527 | 0.4075 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14119.189 | 0.6527 | 0.4075 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14119.189 | 0.3521 | -0.1535 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14119.189 | 0.3521 | -0.1535 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14119.189 | 0.1743 | -0.5255 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14119.189 | 0.1743 | -0.5255 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14119.189 | 0.4442 | 0.0253 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14119.189 | 0.4442 | 0.0253 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14233.189 | 0.9821 | 0.9068 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14233.189 | 0.9821 | 0.9068 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14233.189 | 0.9929 | 0.9626 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14233.189 | 0.9929 | 0.9626 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14233.189 | 0.9894 | 0.9444 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14233.189 | 0.9894 | 0.9444 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14233.189 | 0.9974 | 0.9863 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14233.189 | 0.9974 | 0.9863 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14233.189 | 0.9948 | 0.9728 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14233.189 | 0.9948 | 0.9728 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14233.189 | 0.5558 | -0.5771 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14233.189 | 0.5558 | -0.5771 | 0.3780 |