Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14233.189 | 0.3214 | -0.9007 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14233.189 | 0.3214 | -0.9007 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14233.189 | 0.1534 | -0.9860 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14233.189 | 0.1534 | -0.9860 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14233.189 | 0.7531 | -0.0555 | 0.3780 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14233.189 | 0.7531 | -0.0555 | 0.3780 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10696.145 | 1.0173 | 1.1059 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10696.145 | 1.0173 | 1.1059 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10696.145 | 0.9623 | 0.7809 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10696.145 | 0.9623 | 0.7809 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10696.145 | 0.9849 | 0.9102 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10696.145 | 0.9849 | 0.9102 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10696.145 | 0.9561 | 0.7468 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10696.145 | 0.9561 | 0.7468 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10696.145 | 0.9405 | 0.6620 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10696.145 | 0.9405 | 0.6620 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10696.145 | 0.7437 | -0.1813 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10696.145 | 0.7437 | -0.1813 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10696.145 | 0.3834 | -0.8890 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10696.145 | 0.3834 | -0.8890 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10696.145 | 0.2796 | -0.9571 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10696.145 | 0.2796 | -0.9571 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10696.145 | 0.1944 | -0.9857 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10696.145 | 0.1944 | -0.9857 | 0.3316 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11855.145 | 0.9705 | 0.8851 | 0.5070 |