Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14194.189 | 0.9511 | 0.9580 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14194.189 | 0.4658 | 0.4472 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14194.189 | 0.4658 | 0.4472 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14194.189 | 0.0430 | -0.4725 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14194.189 | 0.0430 | -0.4725 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14194.189 | 0.0077 | -0.7451 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14194.189 | 0.0077 | -0.7451 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14194.189 | 0.0701 | -0.3512 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14194.189 | 0.0701 | -0.3512 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14194.189 | 0.9278 | 0.9376 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14194.189 | 0.9278 | 0.9376 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14610.189 | 0.9867 | 0.9753 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14610.189 | 0.9867 | 0.9753 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14610.189 | 0.9048 | 0.8229 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14610.189 | 0.9048 | 0.8229 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14610.189 | 0.9661 | 0.9370 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14610.189 | 0.9661 | 0.9370 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14610.189 | 0.9911 | 0.9835 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14610.189 | 0.9911 | 0.9835 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14610.189 | 0.6733 | 0.3861 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14610.189 | 0.6733 | 0.3861 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14610.189 | 0.0482 | -0.8798 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14610.189 | 0.0482 | -0.8798 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14610.189 | 0.0177 | -0.9525 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14610.189 | 0.0177 | -0.9525 | 1.0787 |