Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14607.189 | 0.9656 | 0.9497 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14607.189 | 0.9656 | 0.9497 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14607.189 | 0.8605 | 0.7928 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14607.189 | 0.8605 | 0.7928 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14607.189 | 0.9713 | 0.9581 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14607.189 | 0.9713 | 0.9581 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14607.189 | 0.9407 | 0.9129 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14607.189 | 0.9407 | 0.9129 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14607.189 | 0.6416 | 0.4477 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14607.189 | 0.6416 | 0.4477 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14607.189 | 0.1481 | -0.5022 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14607.189 | 0.1481 | -0.5022 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14607.189 | 0.0254 | -0.8621 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14607.189 | 0.0254 | -0.8621 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14607.189 | 0.0212 | -0.8793 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14607.189 | 0.0212 | -0.8793 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14607.189 | 0.0157 | -0.9029 | 1.3733 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14607.189 | 0.0157 | -0.9029 | 1.3733 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14194.189 | 0.9874 | 0.9893 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14194.189 | 0.9874 | 0.9893 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14194.189 | 0.9143 | 0.9255 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14194.189 | 0.9143 | 0.9255 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14194.189 | 0.9449 | 0.9526 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14194.189 | 0.9449 | 0.9526 | 2.3616 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14194.189 | 0.9511 | 0.9580 | 2.3616 |