Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Methylglyoxal | 0.138 | uM | 13492.184 | 0.9749 | 0.9477 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 0.691 | uM | 13492.184 | 0.9708 | 0.9392 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 3.46 | uM | 13492.184 | 0.9885 | 0.9760 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 17.3 | uM | 13492.184 | 0.9570 | 0.9103 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 86.4 | uM | 13492.184 | 0.8582 | 0.7051 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 432 | uM | 13492.184 | 0.8351 | 0.6573 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 2160 | uM | 13492.184 | 0.4023 | -0.2263 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 10800 | uM | 13492.184 | 0.1082 | -0.8032 | 0.9589 | |||
| BT-474 | HER2amp | Luminal | Methylglyoxal | 54000 | uM | 13492.184 | 0.0072 | -0.9884 | 0.9589 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13153.184 | 1.0001 | 1.0001 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13153.184 | 1.0473 | 1.0391 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13153.184 | 1.0204 | 1.0170 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13153.184 | 0.4003 | 0.3625 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13153.184 | 0.8112 | 0.8321 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 432 | uM | 13153.184 | 0.2748 | 0.1637 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13153.184 | 0.0037 | -0.8091 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13153.184 | 0.0018 | -0.8583 | 2.3850 | |||
| BT-549 | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13153.184 | 0.0004 | -0.9268 | 2.3850 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13157.184 | 1.0085 | 1.0200 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13157.184 | 0.9856 | 0.9660 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13157.184 | 1.0092 | 1.0218 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13157.184 | 1.0059 | 1.0139 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13157.184 | 0.9836 | 0.9615 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 432 | uM | 13157.184 | 0.9696 | 0.9285 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13157.184 | 0.7502 | 0.4258 | 0.8492 |