Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.0213 | uM | 7510.084 | 1.0112 | 1.0258 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.107 | uM | 7510.084 | 1.0474 | 1.1093 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.533 | uM | 7510.084 | 0.8992 | 0.7700 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 2.67 | uM | 7510.084 | 1.0429 | 1.0990 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 13.3 | uM | 7510.084 | 0.9863 | 0.9685 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 66.7 | uM | 7510.084 | 0.9351 | 0.8517 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 333 | uM | 7510.084 | 0.9423 | 0.8679 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.000853 | uM | 7511.084 | 1.0118 | 1.0205 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.00427 | uM | 7511.084 | 0.9993 | 0.9988 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.0213 | uM | 7511.084 | 0.9741 | 0.9548 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.107 | uM | 7511.084 | 0.7084 | 0.4807 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.533 | uM | 7511.084 | 0.7412 | 0.5402 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 2.67 | uM | 7511.084 | 0.7305 | 0.5208 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 13.3 | uM | 7511.084 | 0.7266 | 0.5139 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 66.7 | uM | 7511.084 | 0.7213 | 0.5041 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 333 | uM | 7511.084 | 0.7040 | 0.4726 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.000853 | uM | 7512.084 | 1.0233 | 1.0622 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.00427 | uM | 7512.084 | 1.0162 | 1.0432 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.0213 | uM | 7512.084 | 1.0370 | 1.0991 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.107 | uM | 7512.084 | 1.0718 | 1.1933 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 0.533 | uM | 7512.084 | 1.0700 | 1.1885 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 2.67 | uM | 7512.084 | 1.0784 | 1.2114 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 13.3 | uM | 7512.084 | 1.0757 | 1.2041 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 66.7 | uM | 7512.084 | 1.0925 | 1.2499 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Methotrexate | DHFR | Metabolism | 333 | uM | 7512.084 | 1.0291 | 1.0778 | 0.7511 |