Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 13078.174 | 1.0016 | 1.0053 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 0.000853 | uM | 13078.174 | 0.9591 | 0.8704 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 0.00427 | uM | 13078.174 | 0.7777 | 0.3367 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 0.0213 | uM | 13078.174 | 0.9870 | 0.9585 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 0.107 | uM | 13078.174 | 0.9705 | 0.9062 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 0.533 | uM | 13078.174 | 0.8667 | 0.5901 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 2.67 | uM | 13078.174 | 0.9533 | 0.8524 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 13.3 | uM | 13078.174 | 0.7788 | 0.3396 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Mebendazole | 66.7 | uM | 13078.174 | 0.5668 | -0.1950 | 0.6238 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 0.000171 | uM | 12677.174 | 1.0114 | 1.0229 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 0.000853 | uM | 12677.174 | 0.9897 | 0.9794 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 0.00427 | uM | 12677.174 | 0.9506 | 0.9010 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 0.0213 | uM | 12677.174 | 0.9500 | 0.8999 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 0.107 | uM | 12677.174 | 0.9351 | 0.8701 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 0.533 | uM | 12677.174 | 0.5094 | 0.0182 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 2.67 | uM | 12677.174 | 0.5385 | 0.0765 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 13.3 | uM | 12677.174 | 0.4048 | -0.1909 | 0.9992 | |||
| ZR-75-1 | HR+ | Luminal | Mebendazole | 66.7 | uM | 12677.174 | 0.2927 | -0.4152 | 0.9992 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 0.000171 | uM | 13595.174 | 0.9833 | 0.9820 | 1.8596 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 0.000853 | uM | 13595.174 | 0.9524 | 0.9483 | 1.8596 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 0.00427 | uM | 13595.174 | 0.9536 | 0.9495 | 1.8596 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 0.0213 | uM | 13595.174 | 0.9320 | 0.9257 | 1.8596 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 0.107 | uM | 13595.174 | 0.7234 | 0.6804 | 1.8596 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 0.533 | uM | 13595.174 | 0.4632 | 0.3221 | 1.8596 | |||
| ZR75B | HR+ | Luminal | Mebendazole | 2.67 | uM | 13595.174 | 0.5568 | 0.4598 | 1.8596 |