Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 12714.174 | 0.9505 | 0.7150 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 12714.174 | 0.9497 | 0.7111 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Mebendazole | 0.107 | uM | 12714.174 | 0.9213 | 0.5606 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Mebendazole | 0.533 | uM | 12714.174 | 0.4787 | -0.7847 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Mebendazole | 2.67 | uM | 12714.174 | 0.3870 | -0.8868 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Mebendazole | 13.3 | uM | 12714.174 | 0.3132 | -0.9403 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Mebendazole | 66.7 | uM | 12714.174 | 0.4507 | -0.8206 | 0.3306 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 0.000171 | uM | 12622.174 | 1.0169 | 1.0138 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 0.000853 | uM | 12622.174 | 0.9758 | 0.9800 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 0.00427 | uM | 12622.174 | 0.9938 | 0.9949 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 0.0213 | uM | 12622.174 | 0.9764 | 0.9805 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 0.107 | uM | 12622.174 | 0.9237 | 0.9359 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 0.533 | uM | 12622.174 | 0.4065 | 0.3820 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 2.67 | uM | 12622.174 | 0.3119 | 0.2397 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 13.3 | uM | 12622.174 | 0.3074 | 0.2322 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Mebendazole | 66.7 | uM | 12622.174 | 0.1872 | 0.0053 | 2.4358 | |||
| LY2 | HR+ | Luminal | Mebendazole | 0.000171 | uM | 12627.174 | 1.0235 | 1.0349 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 0.000853 | uM | 12627.174 | 0.9815 | 0.9723 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 0.00427 | uM | 12627.174 | 1.0095 | 1.0142 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 0.0213 | uM | 12627.174 | 0.9648 | 0.9474 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 0.107 | uM | 12627.174 | 0.9879 | 0.9819 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 0.533 | uM | 12627.174 | 0.6493 | 0.4497 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 2.67 | uM | 12627.174 | 0.5245 | 0.2366 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 13.3 | uM | 12627.174 | 0.4715 | 0.1421 | 1.3419 | |||
| LY2 | HR+ | Luminal | Mebendazole | 66.7 | uM | 12627.174 | 0.4071 | 0.0237 | 1.3419 |