Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7483.095 | 1.1836 | 1.1302 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7483.095 | 1.2304 | 1.1613 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7483.095 | 1.1293 | 1.0931 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7483.095 | 0.3651 | 0.3719 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7483.095 | 0.1511 | -0.0138 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7483.095 | 0.1004 | -0.1536 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7483.095 | 0.0581 | -0.3102 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7483.095 | 0.0004 | -0.8965 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7483.095 | 0.0004 | -0.8965 | 2.6732 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7484.094 | 1.0276 | 1.0206 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7484.094 | 0.3896 | 0.4025 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7484.094 | 0.2415 | 0.1713 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7484.094 | 0.1691 | 0.0243 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7484.094 | 0.1496 | -0.0220 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7484.094 | 0.0038 | -0.7545 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7484.094 | 0.0007 | -0.8720 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7484.094 | 0.0039 | -0.7526 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 197 | uM | 7484.094 | 0.0055 | -0.7179 | 2.6561 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7485.095 | 1.0500 | 1.0268 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7485.095 | 0.9565 | 0.9759 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7485.095 | 0.8181 | 0.8933 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7485.095 | 0.3668 | 0.5209 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7485.095 | 0.1761 | 0.2448 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7485.095 | 0.1138 | 0.1048 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7485.095 | 0.0649 | -0.0521 | 3.6625 |