Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7931.017 | 0.9633 | 0.9453 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7931.017 | 0.8090 | 0.7091 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7931.017 | 0.7416 | 0.6024 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7931.017 | 0.6731 | 0.4913 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7931.017 | 0.5989 | 0.3676 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7931.017 | 0.4469 | 0.1008 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7931.017 | 0.2489 | -0.2869 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7931.017 | 0.1353 | -0.5462 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7932.017 | 0.9864 | 0.9746 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7932.017 | 1.0108 | 1.0202 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7932.017 | 1.0068 | 1.0127 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7932.017 | 0.8807 | 0.7764 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7932.017 | 0.6789 | 0.3932 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7932.017 | 0.5930 | 0.2280 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7932.017 | 0.4766 | 0.0013 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7932.017 | 0.2599 | -0.4316 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7932.017 | 0.1244 | -0.7143 | 1.0712 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9972.017 | 0.7322 | 0.5311 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9972.017 | 0.7360 | 0.5379 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9972.017 | 0.9667 | 0.9428 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9972.017 | 0.7645 | 0.5887 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9972.017 | 0.5933 | 0.2785 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9972.017 | 0.5549 | 0.2072 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9972.017 | 0.4413 | -0.0080 | 1.1666 | |
| ZR75B | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9972.017 | 0.2408 | -0.4098 | 1.1666 |