Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7926.017 | 0.9323 | 0.8485 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7926.017 | 0.8822 | 0.7372 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7926.017 | 0.7428 | 0.4317 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7926.017 | 0.3815 | -0.3231 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7926.017 | 0.1970 | -0.6781 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7926.017 | 0.0874 | -0.8709 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 10267.131 | 1.0310 | 1.1652 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 10267.131 | 1.1433 | 1.8320 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 10267.131 | 0.9752 | 0.8736 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 10267.131 | 0.9361 | 0.6846 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 10267.131 | 0.8251 | 0.2137 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 10267.131 | 0.7229 | -0.1393 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 10267.131 | 0.4088 | -0.8043 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 10267.131 | 0.1746 | -0.9785 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 10267.131 | 0.0868 | -0.9965 | 0.3849 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9045.13 | 0.8894 | 0.7863 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9045.13 | 1.1088 | 1.2092 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9045.13 | 0.9123 | 0.8306 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9045.13 | 1.0371 | 1.0714 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9045.13 | 1.0571 | 1.1099 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9045.13 | 0.9826 | 0.9664 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9045.13 | 0.7154 | 0.4483 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9045.13 | 0.3961 | -0.1806 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9045.13 | 0.2325 | -0.5098 | 1.0377 | |
| ZR-75-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7931.017 | 1.0096 | 1.0142 | 1.3488 |