Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7530.093 | 1.0514 | 1.0471 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7530.093 | 1.0252 | 1.0233 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7530.093 | 0.9878 | 0.9886 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7530.093 | 1.1010 | 1.0913 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7530.093 | 1.0133 | 1.0123 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7530.093 | 0.9090 | 0.9134 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7530.093 | 0.3435 | 0.2180 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7530.093 | 0.0117 | -0.7466 | 2.1548 | |
| SUM149PT | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7530.093 | 0.0070 | -0.7995 | 2.1548 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7531.093 | 0.9863 | 0.9924 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7531.093 | 1.0531 | 1.0290 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7531.093 | 0.9998 | 0.9999 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7531.093 | 0.9477 | 0.9704 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7531.093 | 0.9760 | 0.9866 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7531.093 | 0.8730 | 0.9259 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7531.093 | 0.0513 | -0.1238 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7531.093 | 0.0005 | -0.7611 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7531.093 | 0.0005 | -0.7611 | 3.5995 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 10520.1 | 0.9743 | 0.9856 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 10520.1 | 0.9063 | 0.9463 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 10520.1 | 0.8474 | 0.9105 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 10520.1 | 1.0000 | 1.0000 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 10520.1 | 0.9246 | 0.9571 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 10520.1 | 1.0015 | 1.0008 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 10520.1 | 0.2125 | 0.3030 | 3.6151 |