Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10644.139 | 0.9092 | 0.7099 | 0.6077 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10644.139 | 0.8037 | 0.3960 | 0.6077 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10644.139 | 0.7153 | 0.1524 | 0.6077 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10644.139 | 0.7479 | 0.2400 | 0.6077 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 10874.151 | 0.9539 | 0.8777 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10874.151 | 0.9491 | 0.8651 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10874.151 | 0.9973 | 0.9928 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10874.151 | 1.0292 | 1.0785 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10874.151 | 1.0246 | 1.0661 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10874.151 | 0.9562 | 0.8838 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10874.151 | 0.8443 | 0.5949 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10874.151 | 0.7437 | 0.3460 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10874.151 | 0.7246 | 0.3000 | 0.7476 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.000128 | uM | 12220.157 | 0.9947 | 0.9682 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.00064 | uM | 12220.157 | 1.1508 | 2.0509 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.0032 | uM | 12220.157 | 1.1022 | 1.6797 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.016 | uM | 12220.157 | 1.1086 | 1.7267 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.08 | uM | 12220.157 | 0.9738 | 0.8463 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.4 | uM | 12220.157 | 0.9900 | 0.9406 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 2 | uM | 12220.157 | 0.8473 | 0.2151 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 10 | uM | 12220.157 | 0.7146 | -0.2718 | 0.3325 | |
| MX1 | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 50 | uM | 12220.157 | 0.7652 | -0.1057 | 0.3325 | |
| SK-BR-3 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.000128 | uM | 11851.157 | 0.9477 | 0.9282 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.00064 | uM | 11851.157 | 0.9665 | 0.9543 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0032 | uM | 11851.157 | 0.9407 | 0.9186 | 1.4707 |