Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10997.143 | 1.0044 | 1.0136 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10997.143 | 1.0255 | 1.0802 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10997.143 | 1.0436 | 1.1375 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10997.143 | 0.9935 | 0.9799 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10997.143 | 1.0186 | 1.0583 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10997.143 | 0.7580 | 0.2986 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10997.143 | 0.2678 | -0.7434 | 0.6416 | ||
| MCF7 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10997.143 | 0.2216 | -0.8090 | 0.6416 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10998.143 | 0.9943 | 0.9808 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10998.143 | 0.9388 | 0.7995 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10998.143 | 0.9925 | 0.9751 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10998.143 | 1.0000 | 1.0000 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10998.143 | 0.9476 | 0.8277 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10998.143 | 1.0267 | 1.0903 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10998.143 | 0.7747 | 0.3046 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10998.143 | 0.5226 | -0.3249 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10998.143 | 0.3486 | -0.6572 | 0.5976 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12206.143 | 0.9802 | 0.9629 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12206.143 | 0.9684 | 0.9408 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 12206.143 | 1.0122 | 1.0229 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 12206.143 | 1.0004 | 1.0008 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 12206.143 | 1.0109 | 1.0203 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 12206.143 | 1.0171 | 1.0320 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 12206.143 | 0.7739 | 0.5732 | 1.0676 | ||
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 12206.143 | 0.4327 | -0.0876 | 1.0676 |