Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 12112.143 | 0.9923 | 0.9909 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 12112.143 | 0.9320 | 0.9183 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 12112.143 | 0.8050 | 0.7589 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 12112.143 | 0.5981 | 0.4752 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 12112.143 | 0.3121 | 0.0039 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 12112.143 | 0.1704 | -0.2985 | 1.6893 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10753.143 | 0.9866 | 0.9821 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10753.143 | 0.9406 | 0.9198 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 10753.143 | 0.9616 | 0.9482 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 10753.143 | 0.9697 | 0.9593 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 10753.143 | 0.9756 | 0.9672 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 10753.143 | 0.9707 | 0.9607 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 10753.143 | 0.9133 | 0.8824 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 10753.143 | 0.4447 | 0.1632 | 1.4954 | ||
| HCC1187 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 10753.143 | 0.3217 | -0.0631 | 1.4954 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 12000.143 | 0.9480 | 0.8841 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 12000.143 | 0.9135 | 0.8076 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 12000.143 | 0.9644 | 0.9205 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 12000.143 | 0.8817 | 0.7372 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 12000.143 | 0.8881 | 0.7514 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 12000.143 | 0.7646 | 0.4812 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 12000.143 | 0.5665 | 0.0592 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 12000.143 | 0.4375 | -0.2069 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 12000.143 | 0.3759 | -0.3307 | 0.8939 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 12084.143 | 0.9160 | 0.8741 | 1.3499 |