Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF 10F
NM
-
Ibandronate
FDPS
0.48
uM
12254.143
1.0423 1.0597 1.4110
MCF 10F
NM
-
Ibandronate
FDPS
2.4
uM
12254.143
1.0250 1.0353 1.4110
MCF 10F
NM
-
Ibandronate
FDPS
12
uM
12254.143
0.9297 0.8993 1.4110
MCF 10F
NM
-
Ibandronate
FDPS
60
uM
12254.143
0.7648 0.6538 1.4110
MCF 10F
NM
-
Ibandronate
FDPS
300
uM
12254.143
0.6115 0.4114 1.4110
MCF 10F
NM
-
Ibandronate
FDPS
1500
uM
12254.143
0.3718 -0.0080 1.4110
MCF12A
NM
Basal B
Ibandronate
FDPS
0.00384
uM
10817.143
1.0336 1.0425 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
0.0192
uM
10817.143
0.9440 0.9281 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
0.096
uM
10817.143
0.9942 0.9926 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
0.48
uM
10817.143
0.9696 0.9612 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
2.4
uM
10817.143
1.0520 1.0655 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
12
uM
10817.143
0.9628 0.9524 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
60
uM
10817.143
0.9272 0.9062 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
300
uM
10817.143
0.6224 0.4797 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
1500
uM
10817.143
0.2152 -0.2466 1.5734
MCF12A
NM
Basal B
Ibandronate
FDPS
0.00384
uM
12365.143
0.8967 0.9107 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
0.0192
uM
12365.143
0.8831 0.8984 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
0.096
uM
12365.143
0.9277 0.9381 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
0.48
uM
12365.143
0.9300 0.9401 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
2.4
uM
12365.143
0.9552 0.9619 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
12
uM
12365.143
0.9130 0.9251 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
60
uM
12365.143
0.7524 0.7753 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
300
uM
12365.143
0.3765 0.3282 2.3865
MCF12A
NM
Basal B
Ibandronate
FDPS
1500
uM
12365.143
0.1790 -0.0273 2.3865
MCF7
HR+
Luminal
Ibandronate
FDPS
0.00384
uM
10997.143
1.0086 1.0270 0.6416