Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10F | NM | - | Ibandronate | FDPS | 0.48 | uM | 12254.143 | 1.0423 | 1.0597 | 1.4110 | ||
MCF 10F | NM | - | Ibandronate | FDPS | 2.4 | uM | 12254.143 | 1.0250 | 1.0353 | 1.4110 | ||
MCF 10F | NM | - | Ibandronate | FDPS | 12 | uM | 12254.143 | 0.9297 | 0.8993 | 1.4110 | ||
MCF 10F | NM | - | Ibandronate | FDPS | 60 | uM | 12254.143 | 0.7648 | 0.6538 | 1.4110 | ||
MCF 10F | NM | - | Ibandronate | FDPS | 300 | uM | 12254.143 | 0.6115 | 0.4114 | 1.4110 | ||
MCF 10F | NM | - | Ibandronate | FDPS | 1500 | uM | 12254.143 | 0.3718 | -0.0080 | 1.4110 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.00384 | uM | 10817.143 | 1.0336 | 1.0425 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.0192 | uM | 10817.143 | 0.9440 | 0.9281 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.096 | uM | 10817.143 | 0.9942 | 0.9926 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.48 | uM | 10817.143 | 0.9696 | 0.9612 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 2.4 | uM | 10817.143 | 1.0520 | 1.0655 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 12 | uM | 10817.143 | 0.9628 | 0.9524 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 60 | uM | 10817.143 | 0.9272 | 0.9062 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 300 | uM | 10817.143 | 0.6224 | 0.4797 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 1500 | uM | 10817.143 | 0.2152 | -0.2466 | 1.5734 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.00384 | uM | 12365.143 | 0.8967 | 0.9107 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.0192 | uM | 12365.143 | 0.8831 | 0.8984 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.096 | uM | 12365.143 | 0.9277 | 0.9381 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 0.48 | uM | 12365.143 | 0.9300 | 0.9401 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 2.4 | uM | 12365.143 | 0.9552 | 0.9619 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 12 | uM | 12365.143 | 0.9130 | 0.9251 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 60 | uM | 12365.143 | 0.7524 | 0.7753 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 300 | uM | 12365.143 | 0.3765 | 0.3282 | 2.3865 | ||
MCF12A | NM | Basal B | Ibandronate | FDPS | 1500 | uM | 12365.143 | 0.1790 | -0.0273 | 2.3865 | ||
MCF7 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10997.143 | 1.0086 | 1.0270 | 0.6416 |