Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 12319.143 | 1.5349 | 3.5756 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 12319.143 | 0.8362 | 0.4156 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 12319.143 | 0.2900 | -0.8169 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 12319.143 | 0.0956 | -0.9785 | 0.5178 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 0.00384 | uM | 12580.143 | 0.9839 | 0.9856 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 0.0192 | uM | 12580.143 | 1.0022 | 1.0020 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 0.096 | uM | 12580.143 | 1.0080 | 1.0071 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 0.48 | uM | 12580.143 | 1.0302 | 1.0268 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 2.4 | uM | 12580.143 | 1.0208 | 1.0186 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 12 | uM | 12580.143 | 1.0426 | 1.0378 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 60 | uM | 12580.143 | 0.6760 | 0.6782 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 300 | uM | 12580.143 | 0.3047 | 0.1743 | 2.2318 | ||
| MB 157 | Unknown | Unknown | Ibandronate | FDPS | 1500 | uM | 12580.143 | 0.0258 | -0.6113 | 2.2318 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 0.00384 | uM | 11056.143 | 1.0513 | 1.0353 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 0.0192 | uM | 11056.143 | 1.1004 | 1.0680 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 0.096 | uM | 11056.143 | 1.0543 | 1.0373 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 0.48 | uM | 11056.143 | 1.1027 | 1.0694 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 2.4 | uM | 11056.143 | 1.0008 | 1.0006 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 12 | uM | 11056.143 | 1.0297 | 1.0206 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 60 | uM | 11056.143 | 0.9646 | 0.9750 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 300 | uM | 11056.143 | 0.6663 | 0.7355 | 2.8628 | ||
| MCF 10A | NM | Basal B | Ibandronate | FDPS | 1500 | uM | 11056.143 | 0.1346 | -0.0072 | 2.8628 | ||
| MCF 10F | NM | - | Ibandronate | FDPS | 0.00384 | uM | 12254.143 | 1.0401 | 1.0565 | 1.4110 | ||
| MCF 10F | NM | - | Ibandronate | FDPS | 0.0192 | uM | 12254.143 | 1.0495 | 1.0696 | 1.4110 | ||
| MCF 10F | NM | - | Ibandronate | FDPS | 0.096 | uM | 12254.143 | 0.9435 | 0.9193 | 1.4110 |