Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 12206.143 | 0.2732 | -0.4069 | 1.0676 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 12594.143 | 1.0585 | 1.0910 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 12594.143 | 0.9685 | 0.9505 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 12594.143 | 1.0031 | 1.0048 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 12594.143 | 1.1378 | 1.2124 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 12594.143 | 1.0478 | 1.0744 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 12594.143 | 0.9895 | 0.9836 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 12594.143 | 0.5361 | 0.2283 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 12594.143 | 0.1203 | -0.6184 | 1.2787 | ||
| MDA-MB-157 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 12594.143 | 0.0091 | -0.9494 | 1.2787 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10642.143 | 0.9415 | 0.7761 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10642.143 | 0.8901 | 0.5903 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10642.143 | 0.9508 | 0.8107 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10642.143 | 0.9186 | 0.6920 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10642.143 | 0.9188 | 0.6926 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10642.143 | 0.8948 | 0.6066 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10642.143 | 0.7347 | 0.0895 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10642.143 | 0.2469 | -0.8728 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10642.143 | 0.1958 | -0.9195 | 0.5076 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10818.143 | 0.9331 | 0.7905 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10818.143 | 0.8834 | 0.6407 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10818.143 | 0.9363 | 0.8004 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10818.143 | 0.9097 | 0.7194 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10818.143 | 0.9376 | 0.8045 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10818.143 | 0.9337 | 0.7925 | 0.6263 |