Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7547.092 | 0.8285 | 0.6527 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7547.098 | 0.9335 | 0.8720 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7547.098 | 0.7694 | 0.5543 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7547.098 | 0.9166 | 0.8393 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7547.098 | 0.8402 | 0.6916 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7547.098 | 0.9027 | 0.8125 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7547.098 | 0.8530 | 0.7165 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7547.098 | 0.7878 | 0.5901 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7547.098 | 0.5504 | 0.1263 | 1.0399 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7547.098 | 0.0507 | -0.8863 | 1.0399 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7552.098 | 0.9468 | 0.9100 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7552.098 | 0.9099 | 0.8472 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7552.098 | 0.9410 | 0.9003 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7552.098 | 0.9372 | 0.8937 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7552.098 | 0.8792 | 0.7945 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7552.098 | 0.9192 | 0.8630 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7552.098 | 0.8006 | 0.6586 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7552.098 | 0.7281 | 0.5312 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7552.098 | 0.7886 | 0.6377 | 1.1882 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7553.091 | 1.0325 | 1.0667 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7553.091 | 1.0276 | 1.0568 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7553.091 | 1.0472 | 1.0970 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7553.091 | 1.0691 | 1.1421 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7553.091 | 0.9568 | 0.9113 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7553.091 | 0.9170 | 0.8298 | 0.9738 |