Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7534.071 | 1.0048 | 1.0088 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7534.071 | 0.9583 | 0.9226 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7534.071 | 0.9214 | 0.8541 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7534.071 | 0.9925 | 0.9861 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7534.071 | 0.9687 | 0.9420 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7534.071 | 0.9969 | 0.9942 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 24 | uM | 7534.071 | 0.0781 | -0.8111 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 120 | uM | 7534.071 | 0.0501 | -0.8746 | 1.0807 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7534.091 | 1.0494 | 1.0998 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7534.091 | 0.9891 | 0.9779 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7534.091 | 1.0009 | 1.0019 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7534.091 | 1.0009 | 1.0019 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7534.091 | 1.0319 | 1.0645 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7534.091 | 0.9980 | 0.9960 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7534.091 | 0.3230 | -0.3614 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7534.091 | 0.2921 | -0.4231 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7534.091 | 0.0039 | -0.9927 | 0.9898 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7534.098 | 1.0840 | 1.1814 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7534.098 | 1.0487 | 1.1052 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7534.098 | 0.9988 | 0.9973 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7534.098 | 0.9978 | 0.9952 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7534.098 | 1.1050 | 1.2271 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7534.098 | 1.0682 | 1.1474 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7534.098 | 0.8337 | 0.6443 | 0.9286 | |
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7534.098 | 0.1083 | -0.8175 | 0.9286 |