Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7900.001 | 0.9296 | 0.8244 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7900.001 | 1.1823 | 1.4694 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7900.001 | 0.6223 | 0.1009 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7900.001 | 0.9029 | 0.7586 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 7900.001 | 0.5376 | -0.0844 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 7900.001 | 0.6687 | 0.2050 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 7900.001 | 0.6316 | 0.1215 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 7900.001 | 0.2210 | -0.7009 | 0.7944 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7902.001 | 1.2182 | 1.2146 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7902.001 | 0.7082 | 0.6735 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7902.001 | 1.2099 | 1.2069 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7902.001 | 0.8997 | 0.8937 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7902.001 | 0.7818 | 0.7613 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 7902.001 | 0.4488 | 0.3223 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 7902.001 | 0.4761 | 0.3632 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 7902.001 | 0.5401 | 0.4549 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 7902.001 | 0.1773 | -0.1816 | 1.9359 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10266.001 | 1.2501 | 1.6313 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 10266.001 | 0.8677 | 0.6799 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 10266.001 | 1.1531 | 1.3826 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 10266.001 | 1.0158 | 1.0388 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 10266.001 | 0.8214 | 0.5706 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 10266.001 | 0.5088 | -0.1282 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 10266.001 | 0.5284 | -0.0866 | 0.8138 | |
| MDA-MB-436 | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 10266.001 | 0.5100 | -0.1257 | 0.8138 |