Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7870.001 | 0.9983 | 0.9983 | 2.0700 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7870.001 | 0.7439 | 0.7337 | 2.0700 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 7870.001 | 0.7330 | 0.7214 | 2.0700 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 7870.001 | 0.6745 | 0.6536 | 2.0700 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 7870.001 | 0.3899 | 0.2689 | 2.0700 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 7870.001 | 0.0703 | -0.4454 | 2.0700 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9551.001 | 1.0552 | 1.0404 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 9551.001 | 0.9372 | 0.9524 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 9551.001 | 1.0342 | 1.0252 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 9551.001 | 1.0229 | 1.0169 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 9551.001 | 0.6739 | 0.7272 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 9551.001 | 0.5665 | 0.6193 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 9551.001 | 0.5022 | 0.5484 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 9551.001 | 0.3666 | 0.3776 | 2.6913 | |
| MCF 10A | NM | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 9551.001 | 0.1465 | -0.0203 | 2.6913 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7871.001 | 1.1144 | 1.2215 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.000427 | uM | 7871.001 | 0.9542 | 0.9111 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.00213 | uM | 7871.001 | 1.0418 | 1.0810 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0107 | uM | 7871.001 | 1.0872 | 1.1689 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0533 | uM | 7871.001 | 0.8339 | 0.6769 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.267 | uM | 7871.001 | 0.8757 | 0.7583 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 1.33 | uM | 7871.001 | 0.8364 | 0.6819 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 6.67 | uM | 7871.001 | 0.5445 | 0.1092 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 33.3 | uM | 7871.001 | 0.1061 | -0.7729 | 1.0311 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7872.001 | 1.0432 | 1.0631 | 1.3610 |