Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10818.15 | 1.0250 | 1.1158 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12126.16 | 0.9168 | 0.7643 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12126.16 | 0.8731 | 0.6443 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12126.16 | 0.9467 | 0.8480 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12126.16 | 0.9120 | 0.7512 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12126.16 | 0.8882 | 0.6855 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12126.16 | 0.9623 | 0.8921 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12126.16 | 0.8869 | 0.6819 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12126.16 | 0.9172 | 0.7655 | 0.6930 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12126.16 | 0.9404 | 0.8302 | 0.6930 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10643.138 | 1.1016 | 1.4290 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10643.138 | 1.0066 | 1.0264 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10643.138 | 1.0476 | 1.1957 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10643.138 | 1.0534 | 1.2202 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10643.138 | 1.0682 | 1.2834 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10643.138 | 1.1393 | 1.5988 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10643.138 | 1.0299 | 1.1219 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10643.138 | 0.8718 | 0.5185 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10643.138 | 0.8069 | 0.3000 | 0.4981 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10999.15 | 0.9351 | 0.8376 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10999.15 | 1.0365 | 1.0925 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10999.15 | 1.0193 | 1.0488 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10999.15 | 0.9861 | 0.9651 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10999.15 | 0.9755 | 0.9384 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10999.15 | 1.0317 | 1.0804 | 0.7928 |