Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12594.169 | 1.0392 | 1.0553 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12594.169 | 0.9583 | 0.9405 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12594.169 | 0.9600 | 0.9430 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12594.169 | 1.0936 | 1.1311 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12594.169 | 1.0591 | 1.0831 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12594.169 | 1.1299 | 1.1810 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12594.169 | 1.0204 | 1.0288 | 1.4097 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12594.169 | 0.8518 | 0.7849 | 1.4097 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10642.138 | 0.9625 | 0.8685 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10642.138 | 0.9518 | 0.8317 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10642.138 | 0.9401 | 0.7918 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10642.138 | 0.9793 | 0.9270 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10642.138 | 0.9572 | 0.8501 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10642.138 | 0.9363 | 0.7790 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10642.138 | 0.9305 | 0.7594 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10642.138 | 0.9171 | 0.7146 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10642.138 | 0.9774 | 0.9202 | 0.5620 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10818.15 | 0.9738 | 0.8827 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10818.15 | 0.9633 | 0.8366 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10818.15 | 0.9567 | 0.8080 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10818.15 | 0.9340 | 0.7119 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10818.15 | 0.9724 | 0.8764 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10818.15 | 0.9723 | 0.8759 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10818.15 | 0.9458 | 0.7617 | 0.4390 | ||
| MDA-MB-175-VII | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10818.15 | 1.0005 | 1.0023 | 0.4390 |