Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10519.138 | 0.9523 | 0.9097 | 1.0592 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10519.138 | 0.9933 | 0.9873 | 1.0592 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10519.138 | 0.9736 | 0.9500 | 1.0592 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10519.138 | 0.8177 | 0.6540 | 1.0592 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10519.138 | 0.3926 | -0.1726 | 1.0592 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10519.138 | 0.1171 | -0.7360 | 1.0592 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10998.15 | 0.9349 | 0.8457 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10998.15 | 0.9888 | 0.9732 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10998.15 | 1.0128 | 1.0305 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10998.15 | 0.9792 | 0.9504 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10998.15 | 0.9540 | 0.8907 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10998.15 | 0.9374 | 0.8517 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10998.15 | 0.7153 | 0.3412 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10998.15 | 0.4733 | -0.1802 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10998.15 | 0.1056 | -0.8631 | 0.8386 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12206.16 | 0.9446 | 0.8879 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12206.16 | 1.0062 | 1.0126 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12206.16 | 0.9682 | 0.9356 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12206.16 | 0.9825 | 0.9646 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12206.16 | 0.9630 | 0.9250 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12206.16 | 0.7855 | 0.5661 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12206.16 | 0.6683 | 0.3296 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12206.16 | 0.3771 | -0.2552 | 0.9874 | ||
| MDA-MB-134-VI | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12206.16 | 0.0914 | -0.8227 | 0.9874 | ||
| MDA-MB-157 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12594.169 | 1.1137 | 1.1588 | 1.4097 |