Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12001.169 | 0.9521 | 0.8680 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12001.169 | 0.9210 | 0.7839 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12001.169 | 0.9971 | 0.9919 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12001.169 | 0.9775 | 0.9376 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12001.169 | 0.9145 | 0.7664 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12001.169 | 0.7492 | 0.3387 | 0.7194 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10693.15 | 1.0264 | 1.0683 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10693.15 | 0.9564 | 0.8883 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10693.15 | 1.0584 | 1.1516 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10693.15 | 1.0006 | 1.0015 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10693.15 | 1.0312 | 1.0806 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10693.15 | 0.9973 | 0.9930 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10693.15 | 1.0195 | 1.0504 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10693.15 | 0.9164 | 0.7873 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10693.15 | 0.9465 | 0.8632 | 0.7763 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11936.16 | 0.9091 | 0.7982 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11936.16 | 0.8954 | 0.7680 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11936.16 | 0.9245 | 0.8324 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11936.16 | 0.9544 | 0.8984 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11936.16 | 0.9203 | 0.8230 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11936.16 | 0.9656 | 0.9234 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11936.16 | 0.9219 | 0.8265 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11936.16 | 0.8477 | 0.6633 | 0.8962 | ||
| HCC1428 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11936.16 | 0.7925 | 0.5428 | 0.8962 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10872.15 | 0.9255 | 0.9070 | 1.6255 |