Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12379.143 | 0.9735 | 0.8840 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12379.143 | 0.9335 | 0.7161 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12379.143 | 0.9045 | 0.5997 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12379.143 | 0.8572 | 0.4192 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12379.143 | 0.7801 | 0.1508 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12379.143 | 0.9370 | 0.7303 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12379.143 | 0.9299 | 0.7014 | 0.4493 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12379.143 | 0.7279 | -0.0136 | 0.4493 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10938.143 | 0.8599 | 0.7242 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10938.143 | 0.8177 | 0.6410 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10938.143 | 0.7315 | 0.4708 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10938.143 | 0.7665 | 0.5400 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10938.143 | 0.7676 | 0.5420 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10938.143 | 0.6917 | 0.3921 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10938.143 | 0.6636 | 0.3364 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10938.143 | 0.6340 | 0.2778 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10938.143 | 0.5122 | 0.0360 | 1.0173 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12333.143 | 0.8961 | 0.6787 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12333.143 | 0.8874 | 0.6528 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12333.143 | 1.0116 | 1.0372 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12333.143 | 0.9348 | 0.7959 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12333.143 | 0.9338 | 0.7929 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12333.143 | 0.8439 | 0.5253 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12333.143 | 0.8407 | 0.5160 | 0.6265 | |
| MDA-MB-415 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12333.143 | 0.6975 | 0.1255 | 0.6265 |