Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7832.011 | 0.5356 | 0.2958 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7834.075 | 1.0213 | 1.0210 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 7834.075 | 0.9361 | 0.9357 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7834.075 | 0.7587 | 0.7443 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7834.075 | 0.7279 | 0.7088 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7834.075 | 0.6339 | 0.5956 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7834.075 | 0.5409 | 0.4750 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7834.075 | 0.4562 | 0.3556 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7834.075 | 0.4878 | 0.4014 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 722 | uM | 7834.075 | 0.4217 | 0.3039 | 2.0182 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9386.011 | 1.0196 | 1.0257 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9386.011 | 0.9536 | 0.9385 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9386.011 | 0.8543 | 0.8035 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9386.011 | 0.7959 | 0.7216 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9386.011 | 0.7685 | 0.6824 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9386.011 | 0.7207 | 0.6130 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9386.011 | 0.7215 | 0.6142 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9386.011 | 0.7130 | 0.6016 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9386.011 | 0.7359 | 0.6352 | 1.5229 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7841.075 | 0.8735 | 0.5575 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 7841.075 | 1.1076 | 1.4160 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7841.075 | 0.9264 | 0.7363 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7841.075 | 0.8586 | 0.5088 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7841.075 | 0.9159 | 0.7002 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7841.075 | 0.8643 | 0.5274 | 0.5408 |