Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7829.011 | 0.6332 | 0.5674 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7829.011 | 0.1353 | -0.3120 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7829.011 | 0.0864 | -0.4584 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7829.011 | 0.0890 | -0.4497 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7829.011 | 0.0878 | -0.4536 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7829.011 | 0.0760 | -0.4941 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7829.011 | 0.0732 | -0.5043 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7829.011 | 0.0689 | -0.5201 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9376.011 | 1.0214 | 1.0269 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9376.011 | 0.6537 | 0.5284 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9376.011 | 0.2301 | -0.2104 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9376.011 | 0.1973 | -0.2835 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9376.011 | 0.1820 | -0.3193 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9376.011 | 0.1918 | -0.2963 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9376.011 | 0.1390 | -0.4260 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9376.011 | 0.1275 | -0.4566 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9376.011 | 0.1610 | -0.3701 | 1.5809 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7832.011 | 0.9236 | 0.8925 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7832.011 | 0.9449 | 0.9228 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7832.011 | 0.9010 | 0.8602 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7832.011 | 0.7974 | 0.7088 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7832.011 | 0.7329 | 0.6114 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7832.011 | 0.7187 | 0.5897 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7832.011 | 0.5657 | 0.3460 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7832.011 | 0.4882 | 0.2149 | 1.4385 |