Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7904.001 | 0.2328 | -0.2983 | 1.3917 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7904.001 | 0.4069 | 0.0481 | 1.3917 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7904.001 | 0.1210 | -0.5617 | 1.3917 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7905.001 | 1.3901 | 2.1151 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7905.001 | 0.9366 | 0.8312 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7905.001 | 1.2457 | 1.6878 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7905.001 | 0.9650 | 0.9065 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7905.001 | 0.0983 | -0.9118 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7905.001 | 0.0830 | -0.9297 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7905.001 | 0.1269 | -0.8755 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7905.001 | 0.3874 | -0.4415 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7905.001 | 0.0483 | -0.9661 | 0.7433 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7906.001 | 1.0037 | 1.0131 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7906.001 | 0.8506 | 0.5046 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7906.001 | 1.1170 | 1.4299 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7906.001 | 0.9544 | 0.8422 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7906.001 | 0.1014 | -0.9643 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7906.001 | 0.0802 | -0.9764 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7906.001 | 0.1262 | -0.9476 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7906.001 | 0.2275 | -0.8521 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7906.001 | 0.0713 | -0.9808 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7907.001 | 1.1652 | 1.2435 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7907.001 | 0.9379 | 0.9059 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7907.001 | 1.1965 | 1.2886 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7907.001 | 0.9309 | 0.8953 | 1.3308 |