Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.107	uM	7555.098	0.9933	0.9919	1.6495
ZR75B	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.533	uM	7555.098	0.9306	0.9146	1.6495
ZR75B	HR+	Luminal	GSK1838705A	IGF1R	RTK	2.67	uM	7555.098	0.9426	0.9296	1.6495
ZR75B	HR+	Luminal	GSK1838705A	IGF1R	RTK	13.3	uM	7555.098	0.5827	0.4416	1.6495
ZR75B	HR+	Luminal	GSK1838705A	IGF1R	RTK	66.7	uM	7555.098	0.0925	-0.5278	1.6495
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0000853	uM	9047.001	0.9757	0.9370	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	0.000427	uM	9047.001	0.9394	0.8439	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	0.00213	uM	9047.001	0.9345	0.8316	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0107	uM	9047.001	1.0036	1.0094	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0533	uM	9047.001	0.8503	0.6201	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	0.267	uM	9047.001	0.9065	0.7606	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	1.33	uM	9047.001	0.9571	0.8893	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	6.67	uM	9047.001	0.7944	0.4834	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	33.3	uM	9047.001	0.5831	-0.0073	0.7701
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0000853	uM	10002.001	0.9675	0.8806	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	0.000427	uM	10002.001	0.9953	0.9824	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	0.00213	uM	10002.001	0.9605	0.8554	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0107	uM	10002.001	1.0166	1.0624	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0533	uM	10002.001	0.9599	0.8534	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	0.267	uM	10002.001	0.9954	0.9828	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	1.33	uM	10002.001	0.9535	0.8303	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	6.67	uM	10002.001	0.8276	0.4064	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	33.3	uM	10002.001	0.1015	-0.9717	0.5372
184B5	NM	Basal	GSK461364	PLK1	PLK	0.0000853	uM	9095.001	1.0690	1.1320	1.0444
184B5	NM	Basal	GSK461364	PLK1	PLK	0.000427	uM	9095.001	1.0474	1.0907	1.0444

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)