Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7841.075 | 0.8671 | 0.5366 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7841.075 | 0.7313 | 0.1212 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 722 | uM | 7841.075 | 0.6472 | -0.1055 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9402.011 | 1.0700 | 1.4419 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9402.011 | 1.0072 | 1.0430 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9402.011 | 1.0147 | 1.0881 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9402.011 | 1.0639 | 1.4014 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9402.011 | 1.0380 | 1.2327 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9402.011 | 1.1630 | 2.1230 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9402.011 | 0.9642 | 0.7958 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9402.011 | 0.8445 | 0.2145 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9402.011 | 0.7468 | -0.1552 | 0.3388 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7848.011 | 0.9681 | 0.8184 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7848.011 | 1.0013 | 1.0078 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7848.011 | 0.9750 | 0.8565 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7848.011 | 0.7746 | -0.0553 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7848.011 | 0.7044 | -0.2855 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7848.011 | 0.7484 | -0.1464 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7848.011 | 0.7709 | -0.0687 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7848.011 | 0.6856 | -0.3401 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7848.011 | 0.7500 | -0.1409 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7849.011 | 0.9596 | 0.8546 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7849.011 | 0.9985 | 0.9946 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7849.011 | 0.9710 | 0.8951 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7849.011 | 0.8073 | 0.3521 | 0.5467 |