Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7873.04 | 0.0466 | -0.5118 | 2.1738 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7873.04 | 0.0451 | -0.5192 | 2.1738 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10061.049 | 1.0956 | 1.1050 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10061.049 | 1.0390 | 1.0433 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10061.049 | 0.9924 | 0.9915 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10061.049 | 0.3838 | 0.1694 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10061.049 | 0.0726 | -0.5400 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10061.049 | 0.0634 | -0.5738 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10061.049 | 0.0574 | -0.5967 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10061.049 | 0.0632 | -0.5746 | 1.7845 | |
| MCF12A | NM | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10061.049 | 0.0581 | -0.5939 | 1.7845 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7875.012 | 1.0224 | 1.0262 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7875.012 | 0.9922 | 0.9909 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7875.012 | 1.0451 | 1.0524 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7875.012 | 0.8180 | 0.7780 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7875.012 | 0.5419 | 0.3968 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7875.012 | 0.4587 | 0.2669 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7875.012 | 0.4371 | 0.2316 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7875.012 | 0.3997 | 0.1688 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7875.012 | 0.3814 | 0.1371 | 1.7071 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9583.012 | 1.0505 | 1.0876 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9583.012 | 1.1032 | 1.1786 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9583.012 | 1.0736 | 1.1276 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9583.012 | 1.0084 | 1.0147 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9583.012 | 0.8114 | 0.6671 | 1.1482 |