Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9376.024 | 0.1287 | -0.3874 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9376.024 | 0.1312 | -0.3805 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9376.049 | 0.9788 | 0.9779 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9376.049 | 1.0179 | 1.0185 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9376.049 | 1.0032 | 1.0033 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9376.049 | 0.8631 | 0.8526 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9376.049 | 0.5024 | 0.3982 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9376.049 | 0.4836 | 0.3707 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9376.049 | 0.5472 | 0.4617 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9376.049 | 0.2088 | -0.1143 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9376.049 | 0.2150 | -0.1009 | 1.9229 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7832.04 | 1.0563 | 1.0868 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7832.04 | 1.0463 | 1.0715 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7832.04 | 1.1360 | 1.2081 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7832.04 | 0.5391 | 0.2384 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7832.04 | 0.2602 | -0.2964 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7832.04 | 0.2343 | -0.3513 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7832.04 | 0.2309 | -0.3586 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7832.04 | 0.2516 | -0.3143 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7832.04 | 0.1973 | -0.4324 | 1.2889 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10262.012 | 1.0242 | 1.0842 | 0.5802 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10262.012 | 1.0381 | 1.1333 | 0.5802 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10262.012 | 1.0605 | 1.2130 | 0.5802 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10262.012 | 0.8427 | 0.4891 | 0.5802 | |
| HCC1937 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10262.012 | 0.3500 | -0.6726 | 0.5802 |