Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10002.012 | 0.4811 | -0.4326 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10002.012 | 0.4661 | -0.4629 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10002.012 | 0.4601 | -0.4746 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10002.012 | 0.4490 | -0.4963 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10002.012 | 0.4515 | -0.4915 | 0.5807 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9095.049 | 0.9888 | 0.9801 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9095.049 | 1.0300 | 1.0535 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9095.049 | 0.8609 | 0.7497 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9095.049 | 0.1438 | -0.6460 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9095.049 | 0.1162 | -0.7073 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9095.049 | 0.1163 | -0.7070 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9095.049 | 0.1115 | -0.7178 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9095.049 | 0.0940 | -0.7576 | 1.1202 | |
| 184B5 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9095.049 | 0.1024 | -0.7384 | 1.1202 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9118.012 | 1.0292 | 1.0575 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9118.012 | 1.1241 | 1.2442 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9118.012 | 1.0161 | 1.0317 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9118.012 | 0.6841 | 0.3761 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9118.012 | 0.5256 | 0.0614 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9118.012 | 0.5058 | 0.0220 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9118.012 | 0.4919 | -0.0055 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9118.012 | 0.4619 | -0.0654 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9118.012 | 0.4578 | -0.0735 | 1.0154 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9120.012 | 1.0267 | 1.0781 | 0.6867 | |
| 600MPE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9120.012 | 1.0419 | 1.1233 | 0.6867 |