Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9997.024 | 1.0676 | 1.1395 | 0.9704 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9997.024 | 0.8276 | 0.6456 | 0.9704 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9997.024 | 0.4476 | -0.1265 | 0.9704 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9997.049 | 0.9879 | 0.9787 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9997.049 | 1.0004 | 1.0006 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9997.049 | 1.0152 | 1.0266 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9997.049 | 1.0084 | 1.0146 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9997.049 | 0.9049 | 0.8325 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9997.049 | 0.9429 | 0.8997 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9997.049 | 0.9947 | 0.9907 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9997.049 | 0.9793 | 0.9637 | 1.1423 | |
| ZR75B | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9997.049 | 0.8815 | 0.7909 | 1.1423 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9047.012 | 0.9518 | 0.8734 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9047.012 | 0.9799 | 0.9470 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9047.012 | 0.3990 | -0.4079 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9047.012 | 0.3963 | -0.4132 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9047.012 | 0.3817 | -0.4415 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9047.012 | 0.3789 | -0.4470 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9047.012 | 0.3730 | -0.4584 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9047.012 | 0.3856 | -0.4340 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9047.012 | 0.3706 | -0.4629 | 0.7549 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10002.012 | 0.9664 | 0.8858 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10002.012 | 0.9757 | 0.9170 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10002.012 | 0.4965 | -0.4010 | 0.5807 | |
| 184A1 | NM | Basal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10002.012 | 0.4686 | -0.4579 | 0.5807 |