Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7912.016 | 0.3794 | -0.7859 | 0.4337 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7914.016 | 0.9467 | 0.9337 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7914.016 | 0.9479 | 0.9352 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7914.016 | 0.8550 | 0.8160 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7914.016 | 0.9787 | 0.9737 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7914.016 | 0.9072 | 0.8836 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7914.016 | 0.9327 | 0.9160 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7914.016 | 0.8318 | 0.7856 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7914.016 | 0.5998 | 0.4600 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7914.016 | 0.2337 | -0.1829 | 1.6240 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9759.019 | 1.0002 | 1.0003 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9759.019 | 0.9307 | 0.8977 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9759.019 | 0.9547 | 0.9333 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9759.019 | 0.9731 | 0.9605 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9759.019 | 0.9877 | 0.9820 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9759.019 | 0.9143 | 0.8731 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9759.019 | 0.8242 | 0.7364 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9759.019 | 0.4837 | 0.1759 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9759.019 | 0.2630 | -0.2468 | 1.3677 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9760.024 | 1.0163 | 1.0318 | 1.0234 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9760.024 | 0.9750 | 0.9512 | 1.0234 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9760.024 | 0.9932 | 0.9868 | 1.0234 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9760.024 | 0.5748 | 0.1642 | 1.0234 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9760.024 | 1.0381 | 1.0744 | 1.0234 | |
| SK-BR-3 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9760.024 | 0.9615 | 0.9247 | 1.0234 |