Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9583.132 | 0.8824 | 0.8031 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9583.132 | 0.9413 | 0.9022 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9583.132 | 0.7665 | 0.6045 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9583.132 | 0.8418 | 0.7341 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9583.132 | 1.0149 | 1.0247 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9583.132 | 0.9672 | 0.9456 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9583.132 | 0.8008 | 0.6638 | 1.2070 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9583.132 | 0.9583 | 0.9306 | 1.2070 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7876.016 | 0.9642 | 0.9323 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7876.016 | 1.0141 | 1.0267 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7876.016 | 0.9956 | 0.9917 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7876.016 | 1.0038 | 1.0072 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7876.016 | 1.0824 | 1.1555 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7876.016 | 1.0089 | 1.0168 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7876.016 | 0.9429 | 0.8918 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7876.016 | 1.0146 | 1.0275 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7876.016 | 0.8473 | 0.7100 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 10077.049 | 1.2081 | 1.8310 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 10077.049 | 0.9382 | 0.7787 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 10077.049 | 1.1643 | 1.6454 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 10077.049 | 1.0613 | 1.2311 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 10077.049 | 1.1201 | 1.4635 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 10077.049 | 1.0189 | 1.0699 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 10077.049 | 1.0995 | 1.3811 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 10077.049 | 1.0559 | 1.2105 | 0.5440 |