Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 10061.049 | 0.9834 | 0.9813 | 1.7845 | |
| MCF12A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 10061.049 | 0.9664 | 0.9621 | 1.7845 | |
| MCF12A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 10061.049 | 0.9251 | 0.9146 | 1.7845 | |
| MCF12A | NM | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 10061.049 | 0.3645 | 0.1362 | 1.7845 | |
| MCF12A | NM | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 10061.049 | 0.2748 | -0.0303 | 1.7845 | |
| MCF12A | NM | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 10061.049 | 0.0156 | -0.8055 | 1.7845 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7874.016 | 0.9468 | 0.9326 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7874.016 | 0.9623 | 0.9523 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7874.016 | 0.8919 | 0.8615 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7874.016 | 1.0309 | 1.0385 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7874.016 | 0.9637 | 0.9542 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7874.016 | 0.9913 | 0.9891 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7874.016 | 1.0100 | 1.0125 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7874.016 | 0.9653 | 0.9561 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7874.016 | 0.7630 | 0.6879 | 1.5947 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7875.016 | 0.9627 | 0.9537 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7875.016 | 0.9292 | 0.9115 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7875.016 | 1.0173 | 1.0213 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7875.016 | 0.9565 | 0.9459 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7875.016 | 1.0082 | 1.0100 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7875.016 | 0.9445 | 0.9309 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7875.016 | 0.9580 | 0.9478 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7875.016 | 0.8639 | 0.8276 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7875.016 | 0.5152 | 0.3292 | 1.6229 | |
| MCF7 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9583.132 | 1.0048 | 1.0080 | 1.2070 |