Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7803.016 | 1.0095 | 1.0067 | 2.8300 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7803.016 | 1.0056 | 1.0039 | 2.8300 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7803.016 | 0.9756 | 0.9826 | 2.8300 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7803.016 | 0.8993 | 0.9263 | 2.8300 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7803.016 | 0.7157 | 0.7771 | 2.8300 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7803.016 | 0.3463 | 0.3750 | 2.8300 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7804.016 | 0.9847 | 0.9867 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7804.016 | 0.9647 | 0.9691 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7804.016 | 0.9959 | 0.9965 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7804.016 | 1.0001 | 1.0001 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7804.016 | 1.0121 | 1.0105 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7804.016 | 0.9346 | 0.9422 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7804.016 | 0.9403 | 0.9473 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7804.016 | 0.8116 | 0.8268 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7804.016 | 0.2566 | 0.1086 | 2.3055 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9024.016 | 1.0352 | 1.0214 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9024.016 | 0.9949 | 0.9969 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9024.016 | 1.0150 | 1.0092 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9024.016 | 0.9727 | 0.9830 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9024.016 | 0.9780 | 0.9863 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 9024.016 | 0.9480 | 0.9673 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 9024.016 | 0.8727 | 0.9178 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 9024.016 | 0.8030 | 0.8691 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 9024.016 | 0.3406 | 0.4348 | 3.2430 | |
| BT-549 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 10261.024 | 1.0057 | 1.0052 | 2.1838 |