Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF12A	NM	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0213	uM	12365.167	0.9850	0.9851	2.0273
MCF12A	NM	Basal B	FTase Inhibitor I	Ftase	MAPK	0.107	uM	12365.167	1.0405	1.0395	2.0273
MCF12A	NM	Basal B	FTase Inhibitor I	Ftase	MAPK	0.533	uM	12365.167	0.9957	0.9957	2.0273
MCF12A	NM	Basal B	FTase Inhibitor I	Ftase	MAPK	2.67	uM	12365.167	0.9934	0.9934	2.0273
MCF12A	NM	Basal B	FTase Inhibitor I	Ftase	MAPK	13.3	uM	12365.167	1.1002	1.0964	2.0273
MCF12A	NM	Basal B	FTase Inhibitor I	Ftase	MAPK	66.7	uM	12365.167	1.0839	1.0811	2.0273
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10997.154	0.9510	0.9106	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10997.154	1.0095	1.0173	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10997.154	0.9778	0.9596	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10997.154	0.9320	0.8757	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10997.154	1.0068	1.0123	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10997.154	0.9560	0.9197	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10997.154	0.9905	0.9827	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10997.154	0.9785	0.9609	1.0978
MCF7	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10997.154	0.9904	0.9825	1.0978
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10519.142	0.9114	0.8032	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10519.142	0.9521	0.8935	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10519.142	0.9308	0.8463	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10519.142	0.9316	0.8480	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10519.142	0.9396	0.8657	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10519.142	0.9475	0.8832	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10519.142	0.9617	0.9148	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10519.142	0.9093	0.7987	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10519.142	0.8516	0.6717	0.8963
MDA-MB-134-VI	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10998.154	0.9001	0.7351	0.7412

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)